Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients

About one-third of diabetes patients suffer from renal failure. Therefore, understanding the mechanisms linking diabetes to renal damage (diabetic nephropathy) would benefit patients as it would help in developing new therapeutic targets and strategies. Sirtuin 1 (Sirt1) is a protein that is involved in cellular stress responses and has been implicated in diabetic nephropathy. However, the exact role of renal Sirt1 on the pathogenesis of renal damage in diabetes has not been fully elucidated.

Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients

About one-third of diabetes patients suffer from renal failure. Therefore, understanding the mechanisms linking diabetes to renal damage (diabetic nephropathy) would benefit patients as it would ...

Fri 12 Jan 18 from Medical Xpress

Longevity insights from demographic, phenotypic and genetic studies

Understanding the demographic, phenotypic and genetic features associated with ageing has been the subject of many studies worldwide. Japan offers a unique opportunity for such studies since ...

Fri 12 Jan 18 from Medical Xpress

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