Current CRISPR gene drives are too strong for outdoor use, studies warn

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.As proof of concept, the researchers used the system to disrupt cuticle, wing, and eye development, producing completely yellow, three-eyed and wingless mosquitoes. Their long-term goal is to develop new pest control strategies.

Current CRISPR gene drives are too strong for outdoor use, studies warn

Self-limiting genetic tools already in development may be able to get around concerns surrounding the use of gene drives.

Thu 16 Nov 17 from ScienceNews

Gene drive technologies for ecosystem conservation: Use with care

Scientists working in the vanguard of new genetic technologies have issued a cautionary call to ensure that possible applications in conservation will only affect local populations. In an article ...

Thu 16 Nov 17 from Phys.org

Making mosquitoes self-destruct

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of ...

Tue 14 Nov 17 from Phys.org

Making mosquitoes self-destruct, Tue 14 Nov 17 from Eurekalert

This Gene-Editing Tech Might Be Too Dangerous To Unleash

With gene drives, scientists are trying to supercharge evolution to eradicate malaria and save endangered species from extinction. But is this DARPA-funded tech safe enough to test in the wild? ...

Thu 16 Nov 17 from Wired Science

Scientists create yellow, three-eyed, wingless mosquitoes by using gene editing tool

Researchers have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, ...

Tue 14 Nov 17 from ScienceDaily

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