Inhibiting serotonin in gut could cure osteoporosis
Finding, in animal model, offers proof of principle that inhibiting serotonin in the gut could become a novel treatment for 10s of millions of osteoporosis sufferersAn investigational drug that inhibits serotonin synthesis in the gut, administered orally once daily, effectively cured osteoporosis in mice and rats reports an international team led by researchers from Columbia University Medical Center, in the Feb. 7 issue of Nature Medicine. Serotonin in the gut has been shown in recent research to stall bone formation. The finding could lead to new therapies that build new bone; most current drugs for osteoporosis can only prevent the breakdown of old bone."New therapies that inhibit the production of serotonin in the gut have the potential to become a novel class of drugs to be added to the therapeutic arsenal against osteoporosis," said Gerard Karsenty, M.D., Ph.D., chair of the Department of Genetics and Development at Columbia University College of Physicians and Surgeons, lead author of the pap
Inhibiting serotonin in gut could cure osteoporosis
An investigational drug that inhibits serotonin synthesis in the gut, administered orally once daily, effectively cured osteoporosis in mice and rats reports an international team led by researchers ...
Sun 7 Feb 10 from PhysOrg
Featured - Inhibiting serotonin in gut could cure osteoporosis, Mon 8 Feb 10 from Labspaces.net
Inhibiting Serotonin Could Cure Osteoporosis, Mon 8 Feb 10 from Laboratory Equipment
Inhibiting Serotonin in Gut Could Cure Osteoporosis, Sun 7 Feb 10 from Newswise
Inhibiting serotonin in gut could cure osteoporosis, Mon 8 Feb 10 from R&D Mag
Inhibiting Serotonin In Gut Could Cure Osteoporosis, Mon 8 Feb 10 from RedOrbit
Inhibiting serotonin in gut could cure osteoporosis, Sun 7 Feb 10 from ScienceDaily
Daily pill helped cure osteoporosis in mice, rats
CHICAGO (Reuters) - A once-a-day pill helped completely rebuild bone in rodents with severe osteoporosis, a finding that could lead to a new class of drugs to treat the brittle-bone disease ...
Mon 8 Feb 10 from Reuters
Blocking Serotonin in Gut Reverses Osteoporosis in Mice (CME/CE)
Blocking serotonin production in the intestine might help restore lost bone mass, rather than just preventing further loss like most current osteoporosis treatments, an animal study suggested.
Sun 7 Feb 10 from MedPageToday
Serotonin May Be a Key to Treat Osteoporosis
An experimental oral drug that targets the hormone serotonin in the gut successfully reversed bone loss and built new bone in mice.
Sun 7 Feb 10 from WebMD
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