Study shows modified blood thinner reduces the impact of traumatic brain injury in mice

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic brain injury (TBI), according to new research findings. Though there is currently no drug therapy to prevent the repercussions that can occur in the days and weeks after TBI, researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mice treated with a modified version of heparin with very low coagulant activity (known as 2-O, 3-O desulfated heparin, ODSH or CX-01) had less brain swelling and inflammation, and less evidence of brain damage, compared to mice that received saline. Results of the study will be presented in Baltimore this week at the annual meeting of the American Association for the Surgery of Trauma.

Study shows modified blood thinner reduces the impact of traumatic brain injury in mice

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic ...

Wed 13 Sep 17 from Medical Xpress

Study shows modified blood thinner reduces the impact of traumatic brain injury in mice, Wed 13 Sep 17 from Eurekalert

Modified Blood Thinner Reduces Impact of Traumatic Brain Injury in Mice

NewsA chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows ...

Wed 13 Sep 17 from Laboratory Equipment

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