Antibiotic ciprofloxacin increases risk of tears and rupture in mouse aortas

A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Baylor College of Medicine's Cardiovascular Research Institute has found that ciprofloxacin, a widely prescribed antibiotic, increases the risk of tears and rupture on the main artery of the body, the aorta, in a mouse model of human aortic aneurysms and dissections (AAD), a disease that carries high risk of death from aortic rupture. The study, which is presented today at the American Heart Association Scientific Sessions 2017, provides insights into the biological mechanism underlying the antibiotic's effects on aortic tissue and suggests that the drug should be used with caution in patients with aortic dilatation.

Antibiotic ciprofloxacin increases risk of tears and rupture in mouse aortas

A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Baylor College of Medicine's Cardiovascular Research Institute has found that ciprofloxacin, a widely prescribed ...

Wed 15 Nov 17 from Medical Xpress

Keyhole surgery more effective than open surgery for ruptured aneurysm

The use of keyhole surgery to repair ruptured abdominal aortic aneurysm is both clinically and cost effective and should be adopted more widely, concludes a randomised trial published by The ...

Tue 14 Nov 17 from Medical Xpress

Abdominal aortic aneurysm linked to dysregulated tryptophan metabolism, study finds

Researchers have found a link between dysregulated tryptophan metabolism and abdominal aortic aneurysm, a life-threatening vascular disease, according to a new study led by Georgia State University.

Mon 13 Nov 17 from Medical Xpress

Abdominal aortic aneurysm linked to dysregulated tryptophan metabolism, study finds, Mon 13 Nov 17 from Eurekalert

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